We are an interactive group, with a strong emphasis on collaboration and cooperation. Faculty are deeply engaged in student mentoring; they provide both oversight and support as students work toward their doctoral degree. The intent is to train students
as future academic peers, and provide a rigorous and engaging intellectual environment for all program members.
Members of the CSD Program currently include 36 full time PhD students and 58 faculty from 10 basic science and clinical
departments. Our faculty members and their labs further
align themselves with, but are not restricted to, 1 or more of 6 research sub-areas under the umbrella of our CSD Program:
Display Name | Research Interest |
---|---|
Richard Benninger | Cellular heterogeneity and electrical synapse plasticity in pancreatic islet function, and dysfunction in diabetes, ageing and therapeutic treatments |
John Caldwell | Functional regulation of ion channels in plasma membranes and Golgi membranes using electrophysiology and molecular biology |
James DeGregori | Cancer Evolution and Cancer Signaling Pathways |
Tobias Eckle | The role of circadian rhythm proteins in cellular adaptation to hypoxia and ischemia |
Thomas Evans | Molecular and cellular mechanisms of early embryonic development in C. elegans using genetic and biochemical approaches |
Katherine Fantauzzo | Receptor tyrosine kinase signaling in mammalian craniofacial development |
Joan Hooper | Cell interactions and gene regulatory networks driving mammalian craniofacial development |
Sujatha Jagannathan | mRNA surveillance in health and disease |
Amanda Law | Molecular, cellular and genetic basis of neurodevelopmental mechanisms involved in risk for schizophrenia and other psychiatric disorders |
Shi-Long Lu | Molecular mechanisms and targeted therapies for squamous cell carcinomas |
Wendy Macklin | Oligodendrocyte development and disease |
Susan Majka | Define how pulmonary mesenchymal vascular progenitor cells (MVPC) regulate microvascular function and adaptive angiogenesis underlying the pathogenesis of chronic lung diseases (CLDs), including emphysema, fibrosis and TSC/LAM. |
Jim McManaman | Mammary gland development and function |
Michael McMurray | Mechanisms of assembly and inheritance of dynamic macromolecular structures: Higher-order septin assemblies in budding yeast |
Jeffrey Moore | Molecular regulation of the microtubule network in cell division and disease |
Chad Pearson | Cell biology of the cytoskeleton: Centriole assembly and function |
Eric Pietras | How inflammation reprograms hematopoietic stem cell (HSC) fate choices |
Rytis Prekeris | Molecular mechanisms regulating the establishment and maintenance of cellular polarity in epithelial cells and neurons |
Tânia Reis | The Genetic Basis of Obesity and Neuronal Control of Energy Balance in Drosophila melanogaster |
Diego Restrepo | Olfactory signal transduction and olfactory sensory coding using electrophysiological, morphological and molecular techniques |
Mary Reyland | Role of protein kinase C delta signaling in apoptosis and cancer |
Olivia Rissland | Post-transcriptional gene regulation; mRNA decay; translation |
Holger Russ | Our laboratory is interested in insulin-producing pancreatic beta cells in health and disease. |
Charles Sagerstrom | Epigenetic and Transcriptional Control of Zebrafish Embryogenesis |
Kunhua Song | Mechanisms governing cardiomyocyte lineage commitment and pathogenesis of cardiomyopathies |
Emily Su | Our lab is primarily focused on molecular mechanisms underlying abnormal placental blood flow and function. |
Kelly Sullivan | Deciphering the role of interferon signaling in Down syndrome using a combination of cell-based and in vivo models |
Matthew Taliaferro | Gene expression; subcellular RNA localization; localized translation in neurons; high-throughput screening; RNA-seq |
Arianne Theiss | Mitochondrial dysfunction in intestinal disease |
Rajeev Vibhakar | Pediatric Oncology & Neuro-Oncology with an emphasis on medulloblastoma. |
Eszter Vladar | How multiciliated cells adopt their cell fate, build cilia and orient the cilia for directional clearance during normal development, regeneration and human disease. |
Xiao-Jing Wang | TGFbeta signaling in cancer and skin development |
Michael Zuscik | Osteoarthritis pathogenesis & treatment; Connections between the gut microbiome and skeletal homeostasis & disease |
Display Name | Research Interest |
---|---|
Linda Barlow | Developmental neurobiology; patterning and formation of sensory organs |
Peter Dempsey | Extracellular Signals in Intestinal Stem Cell Niche |
Susan Majka | Define how pulmonary mesenchymal vascular progenitor cells (MVPC) regulate microvascular function and adaptive angiogenesis underlying the pathogenesis of chronic lung diseases (CLDs), including emphysema, fibrosis and TSC/LAM. |
Eric Pietras | How inflammation reprograms hematopoietic stem cell (HSC) fate choices |
Yosef Refaeli | The role of MYC in the regulation of hematopoietic stem cell self-renewal, proliferation, differentiation and survival |
Dennis Roop | Skin development and disease |
Xiao-Jing Wang | TGFbeta signaling in cancer and skin development |
Michael Zuscik | Osteoarthritis pathogenesis & treatment; Connections between the gut microbiome and skeletal homeostasis & disease |
Display Name | Research Interest |
---|---|
Bruce Appel | Development and repair of the vertebrate nervous system |
Linda Barlow | Developmental neurobiology; patterning and formation of sensory organs |
Emily Bates | Mechanisms underlying developmental signaling in mice and in fruit flies and genetic modeling of human disorders |
Kristen Boyle | Clinical interventions combined with mechanistic investigations by using primary human cell culture models |
Joseph Brzezinski | Development of the mammalian retina |
David Clouthier | Signaling pathways regulating craniofacial and cardiovascular development |
Thomas Evans | Molecular and cellular mechanisms of early embryonic development in C. elegans using genetic and biochemical approaches |
Katherine Fantauzzo | Receptor tyrosine kinase signaling in mammalian craniofacial development |
Thomas Finger | Development and organization of taste and smell |
Santos Franco | Neural stem cell fate-specification, neurogenesis, cell migration and circuit formation in the developing CNS |
Joan Hooper | Cell interactions and gene regulatory networks driving mammalian craniofacial development |
Amanda Law | Molecular, cellular and genetic basis of neurodevelopmental mechanisms involved in risk for schizophrenia and other psychiatric disorders |
Traci Lyons | Mechanisms of lymphatic mediated metastasis of breast cancer. |
Wendy Macklin | Oligodendrocyte development and disease |
Jamie Nichols | Skeletal development and variability |
Eric Pietras | How inflammation reprograms hematopoietic stem cell (HSC) fate choices |
Rytis Prekeris | Molecular mechanisms regulating the establishment and maintenance of cellular polarity in epithelial cells and neurons |
Tânia Reis | The Genetic Basis of Obesity and Neuronal Control of Energy Balance in Drosophila melanogaster |
Diego Restrepo | Olfactory signal transduction and olfactory sensory coding using electrophysiological, morphological and molecular techniques |
Dennis Roop | Skin development and disease |
Charles Sagerstrom | Epigenetic and Transcriptional Control of Zebrafish Embryogenesis |
Julie Siegenthaler | CNS vascular development and stability |
Kunhua Song | Mechanisms governing cardiomyocyte lineage commitment and pathogenesis of cardiomyopathies |
Emily Su | Our lab is primarily focused on molecular mechanisms underlying abnormal placental blood flow and function. |
Kelly Sullivan | Deciphering the role of interferon signaling in Down syndrome using a combination of cell-based and in vivo models |
Lori Sussel | The main focus of our research is to understand the complex transcriptional networks that regulate development, differentiation and function of the pancreas |
Xiao-Jing Wang | TGFbeta signaling in cancer and skin development |
Trevor Williams | Transcriptional regulation of mouse embryonic development and the role of transcription factors in mammary gland development and breast cancer |
Display Name | Research Interest |
---|---|
Bruce Appel | Development and repair of the vertebrate nervous system |
Linda Barlow | Developmental neurobiology; patterning and formation of sensory organs |
Richard Benninger | Cellular heterogeneity and electrical synapse plasticity in pancreatic islet function, and dysfunction in diabetes, ageing and therapeutic treatments |
Joseph Brzezinski | Development of the mammalian retina |
James DeGregori | Cancer Evolution and Cancer Signaling Pathways |
Katherine Fantauzzo | Receptor tyrosine kinase signaling in mammalian craniofacial development |
Santos Franco | Neural stem cell fate-specification, neurogenesis, cell migration and circuit formation in the developing CNS |
Ethan Hughes | Oligodendrocytes and their Precursors in the Adult Central Nervous System |
Sujatha Jagannathan | mRNA surveillance in health and disease |
Michael McMurray | Mechanisms of assembly and inheritance of dynamic macromolecular structures: Higher-order septin assemblies in budding yeast |
Jeffrey Moore | Molecular regulation of the microtubule network in cell division and disease |
Jamie Nichols | Skeletal development and variability |
Chad Pearson | Cell biology of the cytoskeleton: Centriole assembly and function |
Rytis Prekeris | Molecular mechanisms regulating the establishment and maintenance of cellular polarity in epithelial cells and neurons |
Tânia Reis | The Genetic Basis of Obesity and Neuronal Control of Energy Balance in Drosophila melanogaster |
Holger Russ | Our laboratory is interested in insulin-producing pancreatic beta cells in health and disease. |
Charles Sagerstrom | Epigenetic and Transcriptional Control of Zebrafish Embryogenesis |
David Schwartz | Investigating the genetic and biological determinants of diseases that are influenced by the environment |
Kunhua Song | Mechanisms governing cardiomyocyte lineage commitment and pathogenesis of cardiomyopathies |
Kelly Sullivan | Deciphering the role of interferon signaling in Down syndrome using a combination of cell-based and in vivo models |
Matthew Taliaferro | Gene expression; subcellular RNA localization; localized translation in neurons; high-throughput screening; RNA-seq |
Arianne Theiss | Mitochondrial dysfunction in intestinal disease |
Xiao-Jing Wang | TGFbeta signaling in cancer and skin development |
Michael Zuscik | Osteoarthritis pathogenesis & treatment; Connections between the gut microbiome and skeletal homeostasis & disease |
Display Name | Research Interest |
---|---|
Bruce Appel | Development and repair of the vertebrate nervous system |
Kristin Artinger | Molecular, genetic and developmental mechanisms involved in the patterning of the early spinal cord (neural plate) during vertebrate embryogenesis |
Linda Barlow | Developmental neurobiology; patterning and formation of sensory organs |
Emily Bates | Mechanisms underlying developmental signaling in mice and in fruit flies and genetic modeling of human disorders |
Richard Benninger | Cellular heterogeneity and electrical synapse plasticity in pancreatic islet function, and dysfunction in diabetes, ageing and therapeutic treatments |
Kristen Boyle | Clinical interventions combined with mechanistic investigations by using primary human cell culture models |
Joseph Brzezinski | Development of the mammalian retina |
John Caldwell | Functional regulation of ion channels in plasma membranes and Golgi membranes using electrophysiology and molecular biology |
David Clouthier | Signaling pathways regulating craniofacial and cardiovascular development |
James DeGregori | Cancer Evolution and Cancer Signaling Pathways |
Peter Dempsey | Extracellular Signals in Intestinal Stem Cell Niche |
Tobias Eckle | The role of circadian rhythm proteins in cellular adaptation to hypoxia and ischemia |
Thomas Evans | Molecular and cellular mechanisms of early embryonic development in C. elegans using genetic and biochemical approaches |
Katherine Fantauzzo | Receptor tyrosine kinase signaling in mammalian craniofacial development |
Thomas Finger | Development and organization of taste and smell |
Santos Franco | Neural stem cell fate-specification, neurogenesis, cell migration and circuit formation in the developing CNS |
Adam Green | Investigating novel targets and therapeutic strategies in the treatment of pediatric high-grade glioma (HGG), including diffuse intrinsic pontine glioma (DIPG) |
Joan Hooper | Cell interactions and gene regulatory networks driving mammalian craniofacial development |
Ethan Hughes | Oligodendrocytes and their Precursors in the Adult Central Nervous System |
Sujatha Jagannathan | mRNA surveillance in health and disease |
Amanda Law | Molecular, cellular and genetic basis of neurodevelopmental mechanisms involved in risk for schizophrenia and other psychiatric disorders |
Shi-Long Lu | Molecular mechanisms and targeted therapies for squamous cell carcinomas |
Traci Lyons | Mechanisms of lymphatic mediated metastasis of breast cancer. |
Wendy Macklin | Oligodendrocyte development and disease |
Susan Majka | Define how pulmonary mesenchymal vascular progenitor cells (MVPC) regulate microvascular function and adaptive angiogenesis underlying the pathogenesis of chronic lung diseases (CLDs), including emphysema, fibrosis and TSC/LAM. |
Jim McManaman | Mammary gland development and function |
Michael McMurray | Mechanisms of assembly and inheritance of dynamic macromolecular structures: Higher-order septin assemblies in budding yeast |
Jeffrey Moore | Molecular regulation of the microtubule network in cell division and disease |
Christian Mosimann | How cells acquire their fates during development and how these processes go wrong in congenital disease. |
Jamie Nichols | Skeletal development and variability |
Lee Niswander | Genetic mechanisms of limb, lung, and neural development |
Karin Payne | The therapeutic potential of bone marrow stem cells and induced pluripotent stem cells. |
Chad Pearson | Cell biology of the cytoskeleton: Centriole assembly and function |
Eric Pietras | How inflammation reprograms hematopoietic stem cell (HSC) fate choices |
Rytis Prekeris | Molecular mechanisms regulating the establishment and maintenance of cellular polarity in epithelial cells and neurons |
Yosef Refaeli | The role of MYC in the regulation of hematopoietic stem cell self-renewal, proliferation, differentiation and survival |
Tânia Reis | The Genetic Basis of Obesity and Neuronal Control of Energy Balance in Drosophila melanogaster |
Diego Restrepo | Olfactory signal transduction and olfactory sensory coding using electrophysiological, morphological and molecular techniques |
Mary Reyland | Role of protein kinase C delta signaling in apoptosis and cancer |
Olivia Rissland | Post-transcriptional gene regulation; mRNA decay; translation |
Dennis Roop | Skin development and disease |
Holger Russ | Our laboratory is interested in insulin-producing pancreatic beta cells in health and disease. |
Charles Sagerstrom | Epigenetic and Transcriptional Control of Zebrafish Embryogenesis |
Stephen Santoro | Development and adaptation of the mammalian olfactory system |
David Schwartz | Investigating the genetic and biological determinants of diseases that are influenced by the environment |
Julie Siegenthaler | CNS vascular development and stability |
Kunhua Song | Mechanisms governing cardiomyocyte lineage commitment and pathogenesis of cardiomyopathies |
Emily Su | Our lab is primarily focused on molecular mechanisms underlying abnormal placental blood flow and function. |
Kelly Sullivan | Deciphering the role of interferon signaling in Down syndrome using a combination of cell-based and in vivo models |
Lori Sussel | The main focus of our research is to understand the complex transcriptional networks that regulate development, differentiation and function of the pancreas |
Matthew Taliaferro | Gene expression; subcellular RNA localization; localized translation in neurons; high-throughput screening; RNA-seq |
Arianne Theiss | Mitochondrial dysfunction in intestinal disease |
Rajeev Vibhakar | Pediatric Oncology & Neuro-Oncology with an emphasis on medulloblastoma. |
Eszter Vladar | How multiciliated cells adopt their cell fate, build cilia and orient the cilia for directional clearance during normal development, regeneration and human disease. |
Xiao-Jing Wang | TGFbeta signaling in cancer and skin development |
Trevor Williams | Transcriptional regulation of mouse embryonic development and the role of transcription factors in mammary gland development and breast cancer |
Michael Yeager | How the lung vasculature -blood vessels and particularly lymphatics- operate during episodes of acute and chronic inflammation |
Michael Zuscik | Osteoarthritis pathogenesis & treatment; Connections between the gut microbiome and skeletal homeostasis & disease |
1380 Lawrence Street
Room 1251
Denver, CO 80204
13001 East 17th Place
W5107
Aurora, CO 80045
303-315-2183