BS in Biology, Pennsylvania State University
Rotation Labs: Rytis Prekeris, Eszter Vladar, Jeff Moore
Research: I joined this program with a passion for cell biology and a drive to learn more about it. Each of my rotations were in different areas of focus but each touched on big biological concepts and processes. My thesis tests the model that cells create programs for regulating microtubule dynamics based on the expression of tubulin genes or isotypes, post-translational modifications, and motor proteins that are regulated by these differences and modulate microtubule dynamics.
About Me: I am originally from California but moved to Colorado with my family before college. Coming back to be close to family was an easy decision and now I can spend time with them, my husband, and my dog Sky.
Career Goals: My goal is to become a professor at an institution with a strong research and teaching mission. After I graduated from Penn State with a degree in Biology, I joined an entomology lab as a PRA to gain more experience in scientific research. Now in graduate school, I am doing what I can to prepare myself to be a good mentor and professor. CSD is a great program for developing these skills from program update talks to making lectures for courses to taking workshops for new techniques.
Adam Almeida (he/him)
BS & MS in Biochemistry, Colorado State University
Rotation Labs: Julie Siegenthaler, Ethan Hughes, Wendy Macklin
Research: Oligodendrocytes are a glial cell type in the central nervous system (CNS) that wraps specialized membrane around axons to form structures called myelin sheaths. Myelin sheaths help to modulate the conduction velocity of neuronal action potentials and is therefore critical for achieving the firing patterns necessary to facilitate communication across the CNS. My research is dissecting the underlying mechanisms regulating the number of myelin sheaths made by an individual oligodendrocyte. Using the zebrafish model system, I am quantifying the dynamics of myelin sheath formation and maintenance by combining extensive in vivo time-lapse and longitudinal imaging of individually labeled oligodendrocytes in the spinal cord.
About me: I am a Colorado Native that loves hanging out with family and friends and training the martial art of jiu jitsu.
Amy Briggs (she/her)
BS in Biotechnology, California State University San Marcos
Rotation Labs: Eszter Vladar, Melanie Koenigshoff, Xiao-Jing Wang, James DeGregori
Research: My project is focused on studying the relationship between autophagy and oncogenesis through the decline of tissue maintenance and increase in positive selection of potentially harmful clones in the changing microenvironment. I hope to parse out the mechanism of the role autophagy is playing in this. Tools that I typically use to answer my questions are mouse models coupled with tissue culturing and molecular techniques.
About Me: I was born and raised in San Diego, CA and now I have traded the ocean for the mountains! When I am not in lab I enjoy backpacking, biking and reading. I am also involved with SACNAS in the CU Anschutz chapter where I hope to create a lively community and engaging outreach opportunities.
BS in Biology, University of Oregon
Rotation Labs: Chad Pearson, Lori Sussel, Katie Fantauzzo
Research: I study how the transcription factor NKX2.2 maintains pancreatic alpha cell identity and how its function differs between alpha and beta cells. By understanding the molecular mechanism of NKX2.2 (ie where it binds DNA, what genes does it transcriptionally regulate, what other proteins it interacts with) I can make conclusions about how identity is maintained but also compare mechanisms between different cell types. During my rotation in Dr. Sussel's lab I was inspired to learn how the same transcription factor can work differently in different cell types. The collaborative environment of CSD and at the Barbara Davis Center for Childhood Diabetes have been highlights and a continuing force during my time at CU Anschutz.
About Me: Being from Oregon stoked my love for the outdoors very early and I have carried on my adventures in the Colorado Rockies. I also have been an active musician and look forward to playing out more as COVID eases up. Grad School is a challenging path and I have found that my labmates, PhD mentor and my partner have all been crucial support allies.
Career Goals: I started my lab career in the lab of Dr. Charles Kimmel at the UO studying the role of Mef2ca in zebrafish craniofacial development. I continued that research when I came to colorado to help Dr. Jamie Nichols start his zebrafish lab at CU Anschutz. During my graduate studies I would like to master many molecular and in vivo techniques, expand my science communication skills and increase my analytical and bioinformatic toolbox. After my time at CSD I would like to pursuit work in the sciences that allow me to use informatics analysis to further our understanding of biology and the molecular realm. CSD has my back on every aspect of my short and long term goals by providing relevant classes, facilitating mentorship opportunities and cultivating a supportive environment.
Brenna Dennison (she/her)
BS in Biology, University of Colorado Denver
Rotation Labs: Julie Siegenthaler, Aaron Johnson, Katherine Fantauzzo
BS in Physics, BS in Geophysics, University of Utah
MS in Geophysics, University of Utah
JD, Denver University
Rotation Labs: Julie Siegenthaler, Adam Green
Research: I study chromatin biology, specifically the role of the arginine methyltransferase PRMT5 in histone mutant pediatric brain cancer. During rotations, a combination of a single-cell RNA-Seq project studying embryonic meninges and a project on epigenetic drivers of pediatric brain cancer helped me to identify my area of research interest.
About Me: I'm a Colorado native and when not in the lab like to bicycle, either on the road or gravel. I enjoy working hard with breaks to recharge and pursue many outside interests.
Diane Gumina (she/her)
Rotation Labs: Linda Barlow, Pepper Schedin, Virginia Winn
Research: Our lab’s primary interest is understanding the mechanisms driving impaired fetoplacental angiogenesis associated with fetal growth restriction. My project investigates human fetoplacental endothelial cell-extracellular matrix interactions, and more specifically, integrin complex dynamics in the regulation of angiogenesis. My overarching interests are in developing better diagnostic techniques and treatment modalities for common pregnancy-associated complications.
About me: I am originally from Colorado and completed my undergrad degree at CU Boulder. I enjoy cooking, baking, and traveling.
Maria Hansen (she/her)Sussel Lab
BS in Biology, University of Copenhagen
MS in Human Biology, University of Copenhagen
Rotation Labs: James DeGregori, Richard Benninger, Lori Sussel
Research: My main passion is type 1 diabetes research. In the Sussel lab, we are interested in understanding the transcriptional networks regulating pancreatic development and function. Using human embryonic stem cells (hESCs) as a model system, I study the function of Groucho co-repressors during human pancreatic development. Additionally, I’m interested in understanding the autoimmune attack of the pancreatic beta cells in type 1 diabetes. I utilize a combination of short-read and long-read RNA sequencing to identify splice variants of beta cell genes, which could potentially give rise to neo-epitopes in the type 1 diabetic pancreas.
About me: I am originally from Denmark but moved to Colorado in 2018. I immediately fell in love with the mountains, and I now spend most of my spare time climbing and hiking. I have become somewhat obsessed with climbing 14ers, and I hope to climb all of them over the next couple of years. I am type 1 diabetic myself, which adds an additional layer of complexity to outdoor adventures. I would love to someday work on increasing accessibility to the outdoors (especially mountaineering) for people with chronic diseases.
Career goals: I earned my bachelor’s degree in biology and my master’s degree in human biology at University of Copenhagen. I wrote my master’s thesis in the Serup lab at Novo Nordisk Foundation Center for Stem Cell Biology, where I worked on characterizing the pancreatic progenitor stage during directed differentiation of hESCs into pancreatic beta cells. I moved to Colorado and joined the Russ lab at Anschutz in 2018, where I continued to work on the generation of stem cell-derived beta-like cells.
In addition to understanding the transcriptional programs driving pancreatic development, and understanding the autoimmune pathogenesis of type 1 diabetes, I am passionate about scientific communication. During graduate school, I hope to improve my scientific communication skills and learn how to convey complex scientific information to a much broader audience. I am a firm believer that we need to narrow the gap between scientists and society in order to build public trust in science.
Trevor IsnerBarlow Lab
Rotation Labs: Emily Bates, Linda Barlow, Santos Franco
Bryan Johnson (he/him)
B.S. Evolutionary Biology, University of Iowa,
Rotation Labs: Linda Barlow, James DeGregori, Rytis Prekeris
Research Statement: I am interested in understanding the role the tumor microenvironment plays in regulating metastatic outgrowth of dormant cancer cells. Specifically, how the tumor microenvironment changes with age or in response to insults like viral infection to facilitate the switch from dormant cancer cells to overt metastatic growth.
About me: I was born and raised in Iowa. When I’m not in the lab I enjoy doing Brazilian Jiu-Jitsu and being outdoors. Since moving to Colorado, I have been learning how to fly fish.
Hannah Jones (she/her)Siegenthaler Lab
Rotation Labs: Julie Siegenthaler, Chad Pearson, Linda Barlow
Research: I am fascinated by the mechanisms underlying development of the vasculature in the central nervous system (CNS) and the associated cell types that create a unique niche within the brain. My project in the Siegenthaler Lab focuses on characterizing a subset of fibroblasts that reside on CNS vasculature called perivascular fibroblasts (PVFs). Following CNS injury, PVFs contribute to fibrotic scar formation and secrete factors that coordinate regeneration. However, the developmental origins and homeostatic functions of PVFs are unknown. My goal is to identify the mechanisms underlying recruitment of PVFs to the vasculature during development and use this knowledge to create model systems to study their role in CNS homeostasis and after injury.
About Me: I’m an East-coast transplant; I do miss the ocean, but I can’t complain about Colorado’s majestic mountains! In my spare time you can find me skiing, biking, rock climbing, or hiking. I also enjoy cooking delicious meals, trying new beer, cross-stitching, listening to podcasts, and spending quality time with my partner, Mark, and our cat, Juniper. Beyond lab and my hobbies, I participate in science outreach by volunteering with the Denver Metro Regional Science & Engineering Fair and coordinating outreach activities with Project Bridge.
Career Goals: My ultimate goal is to become a research professor with my own lab and with my own students to teach and mentor. CSD has done a great job in preparing me for this! Within the program, there are multiple opportunities to teach and be involved with mentorship. I’ve developed lectures for CSD courses, I’m a student representative on the CSD curriculum committee, and I am a co-director of the student-run Journal Club. I’ve also had the opportunity to mentor undergraduate & master’s students within my lab and gain formal mentorship training through CSD’s Developing Scholars program. With the support of the program, my thesis mentor, and my thesis committee, I feel thoroughly prepared for the next stop in my career-- obtaining a postdoc position!
Samantha Landgrave (she/her)
TOTTS TL1 Pre-doctoral Award
Rotation Labs: Richard Benninger, Kristen Boyle, Mike Zuscik
Research: My doctoral training research interest involves developing a comprehensive understanding of how parathyroid hormone-related peptide (PTHrP) and type I parathyroid hormone receptor (PTHR1) pathways change and contribute to the development of posttraumatic osteoarthritis.
About Me: I am originally from San Diego, CA. When I am not in lab I love to be outdoors. Colorado has plenty of outdoor activities and things to explore. My support system through graduate school is my family and friends. With the pandemic, it has become very important to me to balance my work life balance to maintain my mental health.
BS in Molecular and Cellular Biology, BA in Biochemistry, University of Arizona
Rotation Labs: Emily Bates, Katie Fantauzzo, Christian Mosimann
Research: In the Mosimann lab, I investigate early heart development and cell fate commitment to cardiac lineages from the uncommitted mesoderm in zebrafish. My project focuses on how different structures of the vertebrate heart acquire their fates and where their progenitor populations come from, and how these processes can go wrong in congenital disease. My favorite resources within CSD are the training courses in grant writing and critical analysis of literature. Grant writing can be intimidating, but having a strong foundation and ample resources gained from these courses makes the process much more approachable and less nerve-wracking. I love that CSD gives me the opportunity to explore my research passions while also supporting my personal and professional goals.
About Me: When I'm not in the lab, I love to go hiking and camping, as well as explore the breweries that Colorado has to offer. I am originally from Arizona, so I love experiencing all the seasons while still soaking in lots of sunshine! My cohort has been the best support system ever since interview weekend. Going through classes and rotations together was challenging, but being able to lean on each other made the transition to graduate school much easier. I serve on the Student Executive Committee as a part of CSD Voices, which allows students to communicate feedback to the program provides students with a way to express their questions or concerns whenever they arise. Additionally, I work with the Denver Metro Regional Science and Engineering Fair on the Mentorship and Outreach Team to make the science fair accessible and exciting for students of all backgrounds in the Denver area.
Career Goals: I received by Bachelors of Science in Molecular and Cellular Biology and my Bachelors of Arts in Biochemistry at the University of Arizona. I transitioned straight from undergrad to graduate school, but took time to travel before I started in the CSD program. My goal in graduate school is to expand our current understanding of the biological processes that contribute to congenital diseases, while also gaining skills in mentorship, grant writing and outreach to continue my path to becoming a fully independent scientist. I am extremely passionate about improving the landscape of academia for both current and future academics, and I am grateful that CSD supports me in these endeavors through both courses and personal and professional support.
Nicole Moss (she/her)NIH F31, RBI RNA Scholar
BS in Biology, University of Oregon
Rotation Labs: Lori Sussel, Jamie Nichols, Linda Barlow
Research: I am fundamentally interested in how changes at the level of mRNAs can modify cellular functions. My work in the Sussel lab combines molecular and bioinformatic approaches to examine alternative splicing changes regulated by Rbfox2 in the pancreatic β cell. Through this work I will uncover both the conserved and novel molecular events regulated by Rbfox2 and their contribution to β cell physiological and pathophysiological processes.
About Me: Before joining CSD I taught high school Biology in Bridgeport, CT as a member of Teach For America and earned a master’s in Biology at the Oregon Institute of Marine Biology in Charleston, OR.
BS Biological Sciences, Molecular and Cellular Biology Concentration
Rotation Labs: Emily Bates, Julie Siegenthaler, Kelly Sullivan
Research: Hi, my name is Kyle and I am originally from California! I grew up in a really small town near Yosemite where I had amazing access to hiking and skiing. I moved to San Diego for college where I fell in love with biology. When I'm not in lab I love to go to the movies and visit the Denver Botanic Gardens. I am also involved with the LGBTQ+ Hub on the Anschutz campus, where I meet monthly for the Governance and Leadership Committee to provide input on the Hub's operations and planned activities.
About Me: I research the role of the microtubule cytoskeleton in brain development. I am specifically interested in how microtubules inside of neurons are controlled when exposed to developmental guidance cues. Our floor has two incredible confocal microscopes that make imaging neurons both exciting and fun! With two of these microscopes it is so much easier to find time to image your samples. My original interest was in neuroscience, but after rotating in Dr. Emily Bates' lab I was introduced to developmental biology. Now in my project I can combine my love for the brain with developmental and cellular biology.
Career Goals: I'm still thinking hard about my career goals! During my undergraduate education I worked for a year at Thermo Fisher Scientific in Carlsbad, CA. This was great exposure to a career in biotech, and I could see myself returning to that field. However, I do love bench science and mentoring students so I could envision myself as a PI at a primarily undergraduate institution. While we don't have undergraduate students on this campus CSD does offer unique teaching opportunities for students, and during the summer we bring undergraduate students into labs where we can get mentorship opportunities.
Sylvia Nunez (she/her)
Rotation Labs: Katie Fantauzzo, Stephen Santoro, Santos Franco, Charles Sagerstrom
Research: Developmental biology is one of my main research interests. I am currently studying cell fate decisions at the midbrain-hindbrain boundary in zebrafish.
About Me: I was born and raised in the Windy City (Chicago, IL), and went to the University of Illinois at Urbana-Champaign for my undergraduate degree where I discovered my passion for biological research. When not in the lab, I love solo traveling, visiting museums, going to concerts, and seeing live theater.
Career Goals: I am still considering all my options to pursue my research interests after graduate school in an academic or industry setting. Scientific outreach is another passion of mine, and so I look forward to becoming more involved in these areas going into my second year!
Yunus Ozekin (he/him)
BS in Biomedical Sciences, Colorado State University
MS in Assisted Reproductive Technologies, Colorado State University
Rotation Labs: Emily Bates, Jamie Nichols, Trevor Williams
Research: My thesis work in the lab of Dr. Emily Bates focuses on understanding how cells use electrical signals to control developmental signaling to properly form a face. Although not traditionally thought of as an excitable tissue, the developing craniofacial complex is susceptible to ion channel mutations in organisms from humans to mice to frogs. My project focuses on deciphering how a specific potassium channel, Kir2.1, intersects with Bone Morphogenetic Protein (BMP) signaling to mediate formation of the craniofacial skeleton, with a particular interest on palatal development.
About Me: I am from Colorado through and through. I grew up just down the road in Aurora, CO. I completed my undergraduate and masters degrees at Colorado State University in Fort Collins, CO. In my free time I enjoy exploring the great outdoors, fishing, painting, and traveling.
Tina Piarowski (she/her)T32 Appointee; NSF-GRFP Honorable Mention
BS Genetics, Cellular and Developmental Biology, Arizona State University
Rotation Labs: Linda Barlow, Melanie Koenigshoff, Sujatha Jagannathan
Research: My research focuses on the role of receptor tyrosine kinases in the taste system, particularly the role of c-Kit it sweet-sensing cells. Using lingual organoids as a model system I found that inhibiting c-Kit leads to a decrease in sweet cell markers. This lead me to my hypothesis that c-Kit is necessary for the differentiation or survival of sweet sensing cells. My thesis work will aim to unravel this relationship using a combination of in vitro organoid models and in vivo work. I was inspired to join the Barlow lab because the sense of taste is central to the human experience, and understanding the cellular and molecular mechanisms mediating taste could help improve the quality of life of people who have lost their sense of taste due to disease or drug treatments.
About Me: In my free time I enjoy hiking, biking, figure skating and hanging out with my cat. I grew up in the suburbs of Chicago before moving to Phoenix for college. After graduating I moved to Denver for graduate school in the CSD program, where I have grown close with my classmates and colleagues. Like many others in CSD, I prioritize work/life balance and usually spend my weekends relaxing or exploring Colorado!
Career Goals: I attended Arizona State University for my undergraduate degree, where I majored in Genetics, Cellular and Developmental Biology with minors in French and Global Health. I took a gap semester after graduating to work as a PRA, which was a great reset that re-energized me before heading to graduate school. During graduate school my goals are to get practice presenting my work to different audiences as well as gain experience mentoring students at the bench. CSD offers many opportunities for students to teach and present, and I also worked with our program director Jeff Moore to create the Developing Scholars mentorship program. I'm very excited about all the opportunities within CSD that can prepare students for a wide variety of careers.
B.S. in Natural Sciences, Xavier University
Rotation Labs: Ethan Hughes, Rajeev Vibhakar, Joe Brzezinski
Research Statement: In the Brzezinski lab, I am researching vertebrate retinal development. Specifically, I am using the mouse retina as a model to understand how Otx2, a gene necessary for retinal development, is regulated during the development and maturation of different cell types within the retina. Using in vivo and ex vivo models along with CRISPR technology, I am teasing out mechanisms mediated by non-coding regions of DNA that regulate the expression of this gene across the developing retina.
About Me: Originally from Peoria, IL, I received my Bachelor’s of Science from Xavier University. I then worked for 2 years at the University of Illinois College of Medicine at Peoria conducting research on the progression of brain tumors. While in the CSD program, I plan on improving my skills communicating scientific data and conclusions, enhancing my analytical skills while gaining more experience mentoring students.
Madison Rogers (she/her)NSF-GRFP Honorable Mention, NIH F31
BS in Biology, Duke University
Rotation Labs: Katherine Fantauzzo, Emily Bates, Julie Siegenthaler
Research: I study how biological specificity is defined through cellular signaling via Receptor Tyrosine Kinases during craniofacial development. I love the supportive culture of the Department of Craniofacial Biology here at Anschutz and appreciate all of the insight from students and faculty into my research project!
About Me: I am originally from Colorado, moved away during college, and moved back for grad school. I love Colorado and everything about it! In my free time, I enjoy skiing, hiking, exercising, trying new restaurants, and enjoying all Colorado has to offer. I also love to travel with my family. At Anschutz, I am on several committees, including the Graduate Advisory Committee and the Career Development Advisory Committee, where I enjoy helping students whose position I have been in previously.
Career Goals: I went to undergrad at Duke University where I majored in biology and minored in chemistry and statistics. Going into undergrad, I knew I wanted to be involved in research, but I didn't know what topics I was most interested in. Performing research through various internships (including one through the Gates Center at Anschutz) helped me find my interest in cell signaling and developmental biology. Thus, I matriculated to CSD following my graduation from Duke in 2017. Throughout graduate school, I have developed a love for science writing, and I aspire to achieve a career in scientific writing or medical writing after I graduate. CSD has been very supportive of this goal and has provided me with opportunities to gain further writing skills, particularly through the Advanced Writing Workshop course that a group of students and I co-developed.
Rotation Labs: Lori Sussel, Richard Benninger, Olivia Rissland
Research: Type 1 diabetes is my primary research interest. Outside of the lab I like to attend live music, play disc golf/go hiking with my dog, and love watching movies.
About Me: I attended Colorado Mesa University for my undergraduate degree. During grad school I want to develop the tools and skills to be able to pursue my own scientific questions. After grad school, I plan to continue focusing my research on type 1 diabetes, although what form that will take is undecided.
Wolf Schleicher (he/him)T32 Appointee
Pietras & DeGregori Labs
BS in Molecular, Cellular, and Developmental Biology and Neuroscience
Rotation Labs: My initial research project aims to understand whether and how metabolism and the NLRP3/IL-1beta axis are linked to facilitate selective hematopoietic stem and progenitor cell (HSPC) expansion in clonal hematopoiesis. Tet2- and Dnmt3a-deficiency are the two most common mutations in clonal hematopoiesis, and they result in similar phenotypes of selective HSPC expansion. Previous work in the Pietras Lab has identified a potential link between these two cellular processes in Tet2-deficient mice, so my current work will explore this same link in Dnmt3a-deficient mice.
Research: I consider myself to be a bit of a pop-culture geek, so many of my interests outside of the lab involve playing tabletop games with friends, marathoning Tolkien and Marvel movies, and volunteering with local conventions (when time allows). However, as I've lived in Colorado my whole life, I also love hiking and camping in the mountains. My support system through graduate school is mainly comprised of close friends (with which I play the aforementioned games) and my significant other. As such, I try to maintain a good work/life balance to afford me time with the people I care about, but some weeks are more successful than others. Currently I am not involved in any school/community activities, but as I transition into my second year, I will hopefully get more engaged with CSD program activities.
About Me: My research interests are in stem cell biology and aging, and how these focuses provide a unique perspective of regenerative medicine. As such, my goals during graduate school are to develop an expertise in stem cell biology and aging-associated morbidity. While my current goal after graduate school is to pursue a leadership position in the biotech industry, I may also pursue a career in the academic setting. The diversity of training faculty in CSD provides me the opportunity to receive mentorship that will cater to these career goals, preparing me for either industry or academia. Moreover, CSD workshops, journal clubs, and seminars provide opportunities to collaboratively develop skills, ideas, and interests to help shape my PhD training.
Ali Shilleh (he/him)
B.S in Biochemistry at the University of Massachusetts Boston, Boston, MA,
M.S in Nutrition and Biomedicine at the Technical University of Munich, Munich, Germany.
Rotation Labs: Bruce Appel, Lori Sussel, Holger Russ
Research: The Russ lab is interested in studying the mechanisms driving the development of diabetes in humans. My project focuses on determining the fate of primary human beta cells and stem cell derived beta-like cells (sBC) upon transplantation. These studies are geared toward improving sBC survival in vivo and promote cell therapy for T1D treatment.
About me: I was born in Serbia and grew up in Ramallah, Palestine. I love to ski, rock climb, hike, run, walk my dog (Crni) and travel. Currently, my wife and I are expecting a third member (a healthy girl) to our family in October 2021.
Career goals: I completed my B.S in biochemistry at Umass Boston in Boston, MA. Received my M.S in Nutrition and Biomedicine at the Technical University of Munich in Munich, Germany. I worked as a research assistant for 9 months in the Russ Lab which I ended up joining as a PhD student. My next step is to pursue a postdoc, with the goal of eventually running my own independent research lab.
Adam Soh (he/him)Pearson lab
BS Cell and Molecular Biology, National University of Singapore
Rotation Labs: Lee Niswander, Rytis Prekeris, Chad Pearson
Research: How cells coordinate their hundreds of cilia to enable efficient fluid flow and cellular motility remains unclear. To address this question, we performed quantitative fluorescence light microscopy to study the interplay between cells' cortical architecture and their response to their fluid environment.
About Me: I'm from Singapore! I love biking, fishing and photography!!
Career Goals: I attended college in Singapore before working as a research assistant for a couple of years. I'm currently close to completing my graduate work. I'm aiming to do a post-doc next!
Rotation Labs: Melanie Koenigshoff, Katie Fantauzzo, David Schwartz
Research: I study how airway epithelial stem cells drive pulmonary fibrosis pathogenesis through the integration of diverse signaling and dynamic cues.
About Me: I am originally from North Carolina, which is where I did my undergraduate training (NC State). After undergrad, I worked as a research assistant in Boston prior to moving to Denver for graduate school. Since grad school, I have rescued two dogs which I spend most of my time with when I am not in lab.
Career goals: I plan on continuing in academic science after graduate school as a post-doc. My long-term career goals include starting my own independent research lab at an R1 institution.
Alex Theis (she/her)
Rotation Labs: Tobias Eckle, Tania Reis, Lori Sussel
Research: For my thesis work, I am studying Groucho co-repressors in the context of pancreatic development and beta cell function. Transcription factors recruit Groucho-related proteins (GRGs) to genomic DNA which then repress gene expression by additional recruitment of chromatin modifiers. Previous work demonstrates the necessity of GRGs in the development of many tissues through interactions with transcription factors that are also crucial for pancreatic development and function. I’ve shown that GRG4 can compensate for a loss of GRG3 in the mouse pancreas and that when both are removed, the insulin-producing beta cells fail to proliferate, liver genes become ectopically expressed in pancreatic cells, and mice die early with severe hyperglycemia. Currently, I am trying to uncover the molecular mechanism of Groucho function in this system to determine interacting partners, target genes, and how loss of GRGs affect beta cell development and function.
About Me: I am originally from central Minnesota and went to school in Duluth, MN on Lake Superior (my favorite place on earth). My best friend is my geriatric cat, Kitty. Other than cats, I also love my brewer husband James, other people's dogs, plants, crafts (knitting, sewing, painting), cross country skiing, backpacking and/or glamping, and watching true crime documentaries.
Career Goals: As an undergrad at the University of Minnesota Duluth, I worked in Dr. Matt Andrews's lab studying the genetic and molecular mechanisms of hibernation in the thirteen-lined ground squirrel. I had the opportunity to work full-time in the lab he summer before my senior year on a project I had been working on for 2 years, which led me to pursue graduate school immediately after graduating with my BS. Also during my undergrad, I was a TA for a chemistry lab course for 3 years - another wonderful opportunity to discover my love for teaching. My ultimate career goal is to be a professor at a primary undergraduate institution, where I can combine my passion for mentoring, teaching, and scientific discovery.
Rotation Labs: Jamie Nichols, Rytis Prekeris, Jeff Moore
Research: My graduate research in the Moore lab focuses on the interaction between microtubules, associated proteins, and kinesins within the mitotic spindle. I use budding yeast because of the relative simplicity and elegance of the spindle, its genetic tractability, and the ability to quantify and characterize clear cellular outcomes. I want to combine in vivo and in vitro techniques to elucidate the interactions between and function of the anaphase midzone spindle components.
About Me: Outside of the lab my hobbies include video games and food & travel. I also enjoy attending theater, ballet, and opera shows at the Denver Center for the Performing Arts. And nothing says work/life balance better than a weekday snowboarding trip with friends, discussing science on the ski lifts!
Career Goals: I love the opportunity to share my scientific passion with others. Prior to graduate school I spent five years teaching and working with high school students. I am still committed to teaching, and now I am pursuing a career in academia so I can combine my interests in teaching with my passion for scientific research.
Rotation Labs: Transferred in with Dr. Zuscik's lab
Research: The gut microbiome is an ecosystem of microbes and their byproducts that play an important role in host homeostasis. It is now appreciated that the gut microbiome become dysbiotic in many different disease states. The goal of my thesis is to uncover the mechanisms by which the gut microbiome is involved in osteoarthritis progression. To do this, I utilize different mouse models and in vitro techniques to look at the relationship between the gut microbiota and osteoarthritis. A final layer of my studies is to uncover how inflammation originating in the gut plays a role in osteoarthritis progression.
I am from Adelaide, Australia and came to the USA for college. I attended Century College in Minnesota before finishing my BS at the University of Wisconsin Superior. Outside of lab, I enjoy playing soccer, Australian rules football, and tennis.
Rotation Labs: Amanda Law, Holger Russ, Traci Lyons
Shane Williams (he/him)
BS in Biology, Saint Michael's College
Rotation Labs: Eszter Vladar, Kunhua Song, Xiao-Jing Wang, Peter Dempsey
Research: I’m interested in improving our ability to utilize stem cell derived models to study human organ development and disease. I’m currently generating fluorescent reporter knock-ins to track intestinal organoid development in real time.
About me: I grew up in New Hampshire and moved to Colorado after finishing undergrad in Vermont. I spend most of my free time exploring the Rockies with my wife searching for the perfect campsite or skiing fresh powder. I also seem to like fish since I’m a reef aquarium hobbyist and have recently picked up fly fishing.
|Student Name||Defense Date||Lab||Current Position|
|Anthony Junker||July, 2021||Chad Pearson||Postdoctoral researcher; Gerardo Lab - Emory University|
|Michael Kaufman||July, 2021||Joe Brzezinski|
|Kayt Scott||June, 2021||Bruce Appel||SPIRE Postdoctoral Fellow in Dr. Kacy Gordon's lab, University of North Carolina - Chapel Hill|
|Heather Brown||November, 2020||Lee Niswander||Captain & Application Scientist, Enzo Life Sciences|
|Mark Gutierrez||May, 2020||Santos Franco||Captain & Staff Scientist, United States Army Medical Department|
|Sofia Pezoa||April, 2020||Lee Niswander||Cell Culture Scientist, Invitria|
|Jayne Aiken||April, 2019||Jeffrey Moore||Postdoctoral Fellow; Dr. Erika Holzbaur - UPenn|
|Stephanie Bonney||March, 2019||Julie Siegenthaler||Postdoctoral Fellow; Dr Andy Shih's lab - Seattle Children's Research Institute|
|Tanya Brown||May, 2019||Wendy Macklin||Postdoctoral Fellow; Dr. Jeff Rasmussen's lab - University of Washington|
|Santiago Fregoso||April, 2019||Santos Franco||Postdoctoral Fellow; Dr. Kathleen Millen's lab - Seattle Children's Research Institute|
|Veronica Fregoso||February, 2019||Amanda Law||Postdoctoral Fellow; Dr. Wendy Macklin's lab - Anschutz Medical Campus|
|Alex Liggett||August, 2019||James DeGregori||Postdoctoral Fellow at the Broad Institue, Dr. Vijay Sankaran's lab|
|Eric Peterman||August, 2019||Rytis Prekeris||Postdoctoral Fellow at the University of Washington, Dr. Jeff Rasmussen's lab|
|Caitlin Winkler||April, 2019||Santos Franco||Senior Research Associate, CU Anschutz Medical Campus, Department of Biochemistry and Molecular Genetics|
|Jennifer Jones||May, 2019||Peter Dempsey|
|Ismail Sola||November, 2019||Rajeev Vibhakar|
|Colleen Bartman||June, 2018||Tobias Eckle||Postdoctoral Fellow, Mayo Clinic|
|Colby Fees||October, 2018||Jeffrey Moore||Postdoctoral Fellow; Dr. Bruce Goode's lab - Brandeis University|
|Senthilnath Lakshmana Chetty||November, 2018||Maranke Koster||Postdoctoral Fellow; Dr. Siddhartha Mitra's lab - Anschutz Medical Campus|
|Swati Mishra||February, 2018||Julie Siegenthaler||Postdoctoral Fellow, University of Washington, Dr. Jessica Young's lab|
|Jason Williams||April, 2018||Kristin Artinger||Postdoctoral Fellow, CU Anschutz Medical Campus, Drs. Hanson and Stenmark's labs|
|Jason Dinella||November, 2017||Peter Koch||Scientist position in Reprogramming Biology at Fate Therapeutics, Inc.|
|Andrew Weems||July, 2017||Michael McMurray||Postdoctoral Fellow, UT Southwestern Medical Center, Dr. Gaudenz Danuser's lab|
|Brian Bayless||July, 2016||Chad Pearson||Assistant Professor, Santa Clara University, Biology Department|
|David Castillo-Azofeifa||April, 2016||Linda Barlow||Postdoctoral Fellow, UCSF, Dr. Ophir Klein|
|Heather Ray||April, 2016||Lee Niswander||Assistant Professor, Idaho State University, Department of Biological Sciences|
|Jonathan Wilde||March, 2016||Lee Niswander||Postdoctoral Fellow, MIT, Dr. Guoping Feng's Lab|
|Jinxiang Dai||July, 2015||Wendy Macklin||Postdoctoral Fellow, Fred Hutchinson Cancer Research Center, Dr. Cyrus Ghajar's lab|
|Brad Kubick||December, 2015||Dennis Roop||Fellow, Flagship Pioneering|
|Davalyn Powell||May, 2014||Kristin Artinger||Science Writer at the Buck Institute for Research on Aging|
|Alex Blasky||May, 2013||Bruce Appel||Global Market Development Manager, Thermo Fisher Scientific|
|Dongying Li||December, 2013||Rytis Prekeris||ORISE fellow, FDA National Center for Toxicology Research|
|Brittany Allen-Petersen||May, 2012||Mary Reland||Postdoctoral Fellow, Oregon Health & Sciences Univ, Dr. Rosalie Sears' Lab|
|Francie Barron||May, 2012||David Clouthier||VP Biology and Regulatory Affairs, Nanomedical Diagnostics|
|Aaron Huebner||December, 2012||Dennis Roop||Postdoctoral Fellow, Harvard Medical School, Dr. Konrad Hochedlinger's Lab|
|Jennifer Ikle||May, 2012||David Clouthier||Pediatric Endocrinology Fellow, Washington University|
|John Schiel||December, 2012||Rytis Prekeris||R&D Senior Scientist, Horizon Discovery|
|Ying Zhang||May, 2012||Lee Niswander||Postdoctoral Fellow, Harvard School of Medicine, Dr. Richard Maas' Lab|
|Tariq Adwan||August, 2011||Mary Reyland||Chief Scientific Officer, Alpha Genomix Laboratories|
|Ha Nguyen||May, 2011||Linda Barlow||Hanoi Medical University|
|Jian Jing||May, 2010||Rytis Prekeris||Postdoctoral Fellow, National Jewish Med Research Ctr, Dr. David Schwartz Lab|
|Lai Kuan||December, 2010||Alexander Sorkin||Postdoctoral Researcher, University of Colorado, Department of Pathology|
|Lai Kuan Dionne (Goh)||December, 2010||Alexander Sorkin||Instructor, Department of Cell Biology and Physiology at Washington University in St. Louis|
|David McKean||December, 2010||Lee Niswander||Research Fellow, Harvard Medical School, Seidman Lab, Dept of Genetics|
|Danielle Harlow||May, 2009||Linda Barlow||Medical Director in Multiple Sclerosis at EMD Serono|
|Roslyn Bauer||December, 2008||John Hutton||Science Writer and Editor, JoVE (Journal Visualized Experiments), Sommerville, MA|
|Glenn Simon||December, 2008||Rytis Prekeris||Postdoctoral Fellow, University of Colorado, Department of Pediatrics|
|Agne Taraseviciute (MSTP)||May, 2008, (MD, 5/2010)||Peter Jones||Fellow in Pediatric Hematology/Oncology, Seattle Children's Hospital|
|Christiana Chao||May, 2007, (MD, 5/2009)||Lori Sussel||Residency, Univ of Washington-Seattle, Dept of Pediatrics|
|James Earl||May, 2006, (MD, 5/2008)||Steve Britt||Physician, St. Alphonsus Hospital, Dept of Ophthalmology|
|Denise Birkholz||August, 2005||Steve Britt||Intraoperative Neuromonitoring Tech, PhySIOM, NIDCR-NRSA|
|Jay Gatlin||May, 2005||Karl Pfenninger||Associate Professor, Univ Wyoming-Laramie, Dept of Botony & Molecular Biology|
|Mike Humphries||December, 2005||Mary Reyland||Staff Scientist, Array BioPharma, Boulder, CO|
|Alex Lublin||May, 2005||Tom Evans||Instructor, Mt. Sinai Hospital, NY, Dept of Neuroscience|
|Scott Barbee||May, 2004||Tom Evans||Associate Professor, Univ of Denver, Dept of Biological Sciences|
|Jennifer Gillette||May, 2004||Sheila Nielsen-Preiss||Associate Professor, Univ New Mexico School of Medicine, Dept of Pathology|
|David Kent||December, 2004||Joan Hooper||Postdoctoral Fellow, Univ of Utah|
|Cindy Yee||May, 2003||Tom Finger||Research Scientist, Genetech, San Francisco, CA|
|Luis Miranda||May, 2002||Alex Franzusoff||Postdoctoral Fellow, Beth Israel Deaconess Med Ctr/Harvard, Boston, MA|
|James Witowsky||December, 2002||Johnson||Research Institute of Molecular Pathology, Vienna, Austria|
|Russ Bowler||August, 2001, (MD, 1993, UCSF)||James Crapo||Professor, National Jewish Med Research Ctr, Dept of Pulmonary/Critical Care|
|Josh Hall||December, 2001, (MD, 5/2003)||Tom Finger||Private Practice, Psychiatric & Behavioral Health Clinic, Poway, CA|
|Keith Mikule||August, 2001||Karl Pfenninger||ArQule Biomedical Institute, Inc., Norwood, MA|
|Christine Wu||May, 2001||Howell/Neville||Assistant Professor, UC Anschutz Medical Campus, Dept of Pharmacology|