In 2012, the Bolie Family established the Victor W. and Earleen Bolie Graduate Scholarship fund, which is dedicated to pre-doctoral training in the Molecular Biology Graduate Program. This generous endowment enables our program to fund training activities
that enhance the scientific and professional development of our trainees. Each year we use the Bolie Graduate Scholarship funds to fund:
Bolie Travel Award. Each trainee in Molecular Biology Graduate Program receives one of these awards during their pre-doctoral training, which enables them to travel to national or international conferences and present their work.
Bolie Mini-Sabbatical. The Bolie Mini-Sabbatical enables pre-doctoral trainees to travel for 1-2 weeks to a laboratory outside University of Colorado to learn new techniques and experimental approaches that expand their training beyond the expertise of their thesis laboratory.
Bolie Scholar Award. Each year, three Bolie Scholar Awards are given to outstanding senior pre-doctoral trainees in recognition of their scientific and educational contributions.
I graduated from Colorado State University in 2015 with two simultaneous Bachelor of Science degrees: one in Microbiology and the other in Biomedical Sciences. I discovered my passion for science during undergrad while working in the lab of Dr. Mary Jackson, studying the cell envelope of Mycobacterium tuberculosis. I continued to explore and refine my research interests after graduation while working in industry, gaining experience at both a high-throughput molecular biology production laboratory and a synthetic biology startup.
I chose to pursue my long-standing interest in microbial physiology and metabolism during graduate school. Under the guidance of Dr. Andrés Vázquez-Torres, I have focused my research on understanding the role of arginine metabolism in Salmonella pathogenesis and response to oxidative stress. Excitingly, my recent findings have revealed that arginine metabolism is a previously unknown determinant of virulence that contributes to the antioxidant defenses of Salmonella by preserving pH homeostasis during oxidative stress. Currently, I am actively working to further develop these observations by investigating which arginine catabolism pathways in Salmonella may be important for maintaining pH homeostasis during oxidative stress.
In my free time, I enjoy hiking and backpacking, taking care of my houseplants and garden, spending time with my cats and partner, and playing percussion in the CU Anschutz Orchestra.
I graduated from the University of North Carolina Asheville in 2014 with a degree in Cellular and Molecular Biology before becoming a professional research assistant in the lab of Dr. Sarah Goetz at Duke University, studying primary ciliogenesis (2015-2018). It was here that my love for science and discovery was ignited.
As a student in the Molecular Biology program, I am under the mentorship of Dr. Olivia Rissland. I study how synonymous codon usage impacts post-transcriptional gene expression and have discovered a new regulatory pathway by which the translation of nonoptimal codons inhibits further translation initiation. I am currently determining if this pathway is distinct to nonoptimal codons or ubiquitous across other types of translational slowdowns.
Outside of research, I love hanging out with friends and my partner, puzzling, listening to podcasts, thrifting, volunteering every week with cats at the local animal shelter (if you want to adopt, go to Dumb Friends League!), playing DnD, and getting out in nature.
Bolie Scholar Award Year
|Katie Hoff||The impact of TUBA1A Tubulinopathy mutations on the regulation of microtubule dynamics.||2022|
|Arely Diaz||RNA-binding protein function in fat metabolism using Drosophila melanogaster||2022|
|Juila Ceglowski||TTLL12 Regulates Tubulin and Ciliogenesis in Polarized Epithelia||2022|
|Rachel Jones||Structure and evolution of a distinct class of exoribonuclease-resistant RNA (xrRNA) structures found in Flaviviruses.||2021|
|Linnea Wethekam||Understanding how cells regulate the expression of the α- and β-tubulin and the consequences of expression imbalance.||2021|
|Claire Gillette||The role of RNA-binding proteins in regulating energy homeostasis||2021|
Mechanisms of Nitric Oxide-induced gentamicin tolerance in Salmonella
Membrane trafficking pathways in cell polarization and lumen formation.
mTOR regulation of oligodendrocyte cytoskeleton rearrangement during myelination
Rab GTPase-mediated ubiquitylation in cell migration and invasion.
RNA repair and translational regulation
Molecular Mechanisms Underlying mRNA Localization to Myelin Sheaths
RNA processing regulates the Unfolded Protein Response
Intrinsic control of microtubule dynamics
The role of alternative splicing in B cells
Regulation of cancer cell migration and invasion by Rab40b.
Dynein regulation by its microtubule track and its influence on microtubule dynamics to properly position the mitotic spindle in budding yeast.
Long noncoding RNAs in heterochromatin establishment and maintenance
Determining the method and mechanism by which split ends and alan shepard contribute to fat regulation in Drosophila and whether it has a conserved role in mammalian cells.
Targeting lung cancers
Innate Host Immune Recognition during Human Papillomavirus Infection
The Role of RNA Polymerase II Elongation Control in Transcription Dynamics
The role of phosphorylation in regulating the Scc2 cohesin deposition factor
The functions of Early B Cell Factor 1 (EBF1) in transcriptional repression and human leukemia
Determining the roles of factor H-Related proteins in Complement Regulation
The role of human SPT6 in transcription regulation by RNA polymerase II
Gene-environment interactions influence on the risk for neural tube defect
Allosteric Communication Networks and Enzymatic Regulation as Mediated by Conformational Dynamics in the Cyclophilin Family of Peptidyl-Prolyl Isomerases