Studies in Progress

TITLE: Movement Pattern Training  after Total Knee Arthroplasty

PURPOSE: To determine if the addition of a novel movement pattern training program focused on movement symmetry after total knee arthroplasty improves movement pattern quality and functional outcomes compared to contemporary rehabilitation alone.

FUNDING: NIH AG056585 $3,004,535



TITLE: Progressing Home Health Rehabilitation Paradigms for Older Adults.

PURPOSE: Clinical trial to determine if an interdisciplinary approach to intensive home health rehabilitation, including care transitions and nutritional supplementation, improves physical function and reduces re-hospitalizations more than usual care.

FUNDING: NIH R01 NR016209 $2,946,919


TITLE: Developing Individualized Estimates of Patient Prognosis Following Knee Replacement

PURPOSE: To develop individualized patient prognoses (personalized medicine) for total knee arthroplasty using novel statistical methodologies (patients like me) to better inform clinical intervention targets.

FUNDING: AHRQ R03 HS024316 $100,000


TITLE: Shifting Rehabilitation Paradigms in Skilled Nursing Facilities

PURPOSE: To evaluate whether an interdisciplinary rehabilitation program that integrates principles of physiologic tissue overload in skill nursing facilities is more effective than the standard of care (pragmatic trial that includes implementation science).

FUNDING: VA Spire Award RR&D I21 RX00219 $198,000


TITLE: Improving Function in Older Veterans with Hospital-associated Deconditioning

PURPOSE:  Clinical trial to determine if high-intensity strength and functional training improves outcomes in older adults following hospitalization.

FUNDING: VA Merit Award RR&D I01 RX001978 $1,000,000


TITLE: Advancing Rehabilitation after Total Hip Arthroplasty

PURPOSE: Clinical trial to evaluate the effectiveness of a multi-modal core stabilization program for movement pattern retraining on functional outcomes after THA.

FUNDING: VA Merit Award RR&D I01 RX002251 $1,098,679


TITLE: Physical activity behavior change for older Veterans after dysvascular amputation

PURPOSE: To determine feasibility of a physical-activity behavior-change intervention targeting improved physical activity and reduced disability in Veterans 1-5 years following dysvascular lower limb amputation.

FUNDING: VA SPiRE Award RR&D I21 RX002054 $194,264


TITLE: Advancing Rehabilitation after Total Hip Arthroplasty

PURPOSE: Clinical Trial to evaluate the effectiveness of a multi-modal core stabilization program for movement pattern retraining on functional outcomes after THA.

FUNDING: VA Merit Award RR&D I01 RX002251 $1,098,679


TITLE: Skeletal Muscle Atrophy and Dysfunction Following Total Knee Arthroplasty

PURPOSE: To evaluate skeletal muscle structure and function before and after TKA at multiple anatomic levels with patients randomized to receive NMES or sham control intervention during the first 5 weeks post-surgery.

FUNDING: NIH R01 AG050305 $204,000 (subcontract)


Completed Studies

TITLE: Movement Pattern Training Following Total Knee Arthroplasty  

PURPOSE: To determine if the addition of a novel movement pattern training program focused on movement symmetry after total knee arthroplasty improves movement pattern quality and functional outcomes compared to contemporary rehabilitation alone (translational rehabilitation technology).

FUNDING: NIH R56 AG048943 $382,625


TITLE: Progressive Rehabilitation for Total Knee Arthroplasty       

PURPOSE: Clinical trial to determine if progressive, high intensity rehabilitation after total knee arthroplasty improves strength and functional outcomes compared to traditional rehabilitation.

FUNDING: NIH R01 HD065900 $2,153,770


TITLE: Impact of Physical Therapy on Improving Function and Reducing Hospitalizations in Medicare Home Health Populations

PURPOSE: Health services research to evaluate the relationship between PT service delivery characteristics and either restoration of physical function or hospital admissions in home health settings using a Medicare claims database.

FUNDING: Center on Health Services Training and Research (CoHSTAR) Pilot Study $25,000


TITLE: Determination of pain phenotypes in older adults with knee osteoarthritis

PURPOSE: To establish the strength of the relationship between potential explanatory variables and pain severity in a population of older adults with knee osteoarthritis (OA) and determine whether these clinically measurable variables are representative of distinct pain phenotypes within knee OA.

FUNDING: NIH R21 AG044710 $425,740