Tamim Shaikh, PhD Graduate Program Director
Copy number variation in developmental delay, intellectual disabilities, and related conditions. Genome structure, rearrangements and evolution.
Cheryl Ackert-Bicknell, PhD
Genetics of bone formation, bone quality, and osteoporosis.
Developmental genetics of the neural crest.
Personalized medicine, evolutionary genetics of human populations, and the genetics of asthma.
Molecular mechanisms of pediatric disorders.
Genetics of pigmentation and melanoma risks.
|Martin Breuss, PhD||Genomic and cellular mosaicism: 1] its role in and impact on disease; 2] its use as a lineage mark||Martin.Breuss@cuanschutz.edu|
Pharmacogenomics, genomic studies of nicotine metabolism, ethical, legal, and social implications (ELSI) of genomic research, genomic variation in health and disease.
Genetics of craniofacial and cardiovascular development.
Genomics and tumor suppressor and oncogenes in cancer biology, trisomy 21 and Down syndrome.
Association studies of complex disorders; type 2 diabetes mellitus
Genetic causes of Parkinson's disease. Modeling human genetic diseases with patient-derived induced pluripotent stem cells.
Interests in applications of population genetic theory, statistical modeling, and algorithmic development to improve large-scale, trans-ethnic, and biobank studies.
Statistical method development and application: (1) to increase the utility of large, publicly available genetic databases and (2) for longitudinal, ‘omics studies.
Bioinformatics and computational biology.
|Colleen G. Julian, PhD||Human genetic adaptation and physiologic responses to the hypoxia of high altitude; hypoxia-related vascular disorders of pregnancy.||Colleen.Julian@cuanschutz.edu|
Development and application of statistical methods for analyzing -omics data sets.
|Ethan Lange, PhD||Study design for gene-mapping studies, including the use of multistage study designs and the use of public genetic resources to improve power for gene discovery.||Ethan.Lange@cuanschutz.edu|
Research focuses on the genetic epidemiology of complex traits, primarily regarding cardiovascular disease, obesity, diabetes, and pulmonary-related phenotypes.
Genetics of psychiatric, neurodevelopmental, and behavioral disorders.
Craniofacial developmental genetics and genetic resilience.
Immunogenetics; genetic variation that underpins our differential responses to infection.
The genetic epidemiology of autoimmune diseases and the nutrigenetics and nutrigenomics of type 1 diabetes.
Neurodegenerative diseases, particularly Alzheimer's Disease, and trisomy 21/Down Syndrome.
CNS gene expression in genetic differences in acute alcohol sensitivity and tolerance.
|Sridharan Raghavan, MD, PhD||Study the causes and consequences of cardiometabolic diseases and anthropometric traits, particularly focused on type 2 diabetes mellitus, diabetes complications, height, and adiposity.||Sridharan.Raghavan@cuanschutz.edu|
Etiology, epidemiology and clinical outcomes of type 1 diabetes & cardiovascular complications of both type 1 and type 2 diabetes.
Genetics of skin disease and skin development: stem cell biology.
Holger Russ, PhD
The Russ labs' research focuses on elucidating the underlying molecular and cellular mechanisms that result in the development of autoimmune diabetes in humans. The lab uses stem cell technology and human primary tissues in conjugation with genome engineering to address previously inaccessible biological questions.
Stephanie Santorico, PhD
Methods and Designs in Statistical Genetics and Genetic Epidemiology including High-Dimensional Data, Multivariate Statistical Inference, Genetic Risk Prediction, and Disease Sub-typing, Variance Components Methods, Multivariate Linkage, Family-Based Association Tests, and Meta-Analysis.
Regie Santos-Cortez MD, PhD
Otolaryngology, Identify novel genes for otitis media susceptibility.
Genetics and epigenetics of environmental lung disease
Genetics/Genomic Analysis of the Airway Epithelium in Asthma
Genome variation in human evolution and disease
Interferon signaling in Down syndrome
Genetics studies of inherited cardiomyopathies, polycystic kidney disease, intellectual disabilities, hereditary vascular diseases, Barth syndrome, Danon disease, and lysosomal storage diseases
Biochemical genetics, mitochondrial diseases, and neurogenetics
Transcriptional control of development and cancer
Genetic and biological determinants of environmental and occupational lung disease
Michael Yeager, PhD
|Erin E. Austin, PhD||Building statistical tools to analyze associations between genetic data and phenotypic data. Discover/cultivate interests in electronic health record data, network analysis in the PheWAS setting, gene- variant-level testing of single or muiltiple traits||Erin.E.Austin@UCDENVER.EDU|
|Peter Baker II, MD||Clinical Genetics and Metabolism, Maternal obesity effects offspring energy sensing and metabolism||Peter.BakerII@cuanschutz.edu|
|Judith Gault, PhD||Genetics of cerebral vascular malformations||Judith.Gault@cuanschutz.edu|
|Nancy Hadley-Miller, PhD||Genetics idiopathic scoliosis complex orthopedic disorders||Nancy.Hadley-Miller@cuanschutz.edu|
|Greggory LaBerge, PhD||Forensic Genetics||Greggory.LaBerge@cuanschutz.edu|
|Sandra Martin, PhD||Molecular evolutionary genetics||Sandy.Martin@cuanschutz.edu|
|Shawn E. McCandless, MD||Pathophysiology and Treatment of Medium-Chain Acyl-CoA Dehydrogenase Deficiency||Shawn.Mccandless@cuanschutzedu|
|Luisa Mestroni, MD||Genetics of adult heart disease; cardiomyopathies||Luisa.Mestroni@cuanschutz.edu|
|York E. Miller, MD||Mouse models of lung cancer risk; Use of genetically modified mice to assess potential lung cancer chemoprevention strategies||York.Miller@cuanschutz.edu|
|Tzu Phang, Ph.D.||Bioinformatics education.||Tzu.Phang@cuanschutz.edu|
|Elaine Spector, PhD||Clinical molecular genetics, the transition of research findings to clinical testing||Elaine.Spector@cuanschutz.edu|
Richard Spritz, MD
|Mapping, discovery, and function of disease genes affecting skin, autoimmunity, and craniofacial development||Richard.Spritz@cuanschutz.edu|
|Janet Thomas, MD||Clinical genetics, biochemical genetics, and genetic counseling||Thomas.Janet@childrenscolorado.org|