Structural Biology and Biochemistry Symposium 2012
Translating Structural Biology to Drug Discovery
Our first annual student-organized Structural Biology and Biochemistry Symposium endeavors to arrange a forum of academic and industrial scientists who are leaders in the elucidation, design, and development of therapeutic molecules. Our objective is
to highlight structure based approaches that translate to drug discovery and development. Find out how structural techniques have been successfully applied and are impacting drug discovery both in academics and the biotechnology and pharmaceutical industries.
~ University of Colorado, Denver Anschutz Medical Campus ~ Structural Biology & Biochemistry Program Pharmaceutical Sciences Program Graduate Students
Date: May 9, 2012
Time: 8:00am to 5:00pm
Location: Research Tower RC-2 Hensel-Phelps West Auditorium 12700 E. 19th Ave. Aurora, CO 80045
How to Submit an Abstract
All abstracts must be submitted electronically from the Registration page.
Or submit Abstract to CUStructuralBioSymp@gmail.com.
Abstracts may be submitted beginning March 1, 2012.
The deadline for abstract submission is at midnight - Tuesday, May 1, 2012.
Length and Content of Abstracts
Each abstract should contain a title of the abstract and the names and institutional affiliations of the authors. The author’s name who will be presenting the abstract should be highlighted. Each abstract should contain an introductory sentence indicating the purposes of the study, a brief description of pertinent experimental procedures, a summary of the data, and a statement of the conclusions.
The combined length of the abstract body should not exceed 400 words, not including authors and title.
John M. Stewart Memorial Poster Award
Monetary awards will be granted to the top three students for outstanding posters presented at the Annual Structural Biology and Biochemistry Symposium in memory of John Stewart. Professor Stewart was an internationally renowned leader in the field of peptide chemistry for almost five decades. Professor Stewart made highly significant contributions in many areas of peptide science, most notably in the design of a wide array of potent and orally active therapeutics for low blood pressure.
In remembrance of John Stewart, members of the Symposium Committee will evaluate the scientific quality of the submitted abstract on the basis of the following criteria: novelty of the research, significance of the findings, and clarity.
The poster board assigned to each presenter has an area of 5 feet in width and 4 feet in height. Each presentation should contain a top panel listing the title of the abstract and the names and institutional affiliations of the authors. Any figure or table presented in the poster should include a legend. The recommended font size for normal text should be 16.
Pushpins, tape, and poster numbers will be available at the session.
The poster presentation will be held in the Tri-visible room from 12:45-1:30 pm during which the presenter will be expected to be present. Posters maybe set up at anytime prior between 8:30-10:00 am. Displays maybe taken down at anytime following the session and any display material left after 6:30 pm will be discarded.
8:30am – 9:10am (Hensel Phelps Atrium)
Registration Welcome & Intro
9:10am – 10:00pm (Hensel Phelps West Auditorium)
Richard DiMarchi, PhD Chemical Biotechnology Applied to Endocrine Hormones
10:00am – 10:40pm (Hensel Phelps West Auditorium)
Xiaotian Zhu, PhD Discovery of Ponatinib, A New ABL Inhibitor to Overcome Drug Resistant Mutations
10:55am – 11:30pm (Hensel Phelps West Auditorium)
Sarah Hymowitz, PhD The LTab2 Heterotrimer Binds 2 Copies of the Lymphotoxin-Beta Receptor with Distinct Affinities
11:30am – 12:00pm (Hensel Phelps West Auditorium)
Greg Miknis, PhD Promoting Academic Drug Discovery in Colorado
12:00pm – 2:00pm (Trivisible Conference Room)
Lunch & Poster Session
2:00pm – 2:50pm (Hensel Phelps West Auditorium)
Mark Lemmon, PhD New Lessons in Regulation and Inhibition of Receptor Tyrosine Kinases
2:50pm – 3:30pm (Hensel Phelps West Auditorium)
Guy Vigers, PhD Structure-Based Design of Akt1 Inhibitors
3:30pm – 4:20pm (Hensel Phelps West Auditorium)
Jonathan Moore, PhD SCrystal Structure of the Ectodomain Complex of the CGRP Receptor: Insights into Antagonism of a Class B GPCR
4:30pm – 6:30pm (Hensel Phelps Atrium)
John M. Steward Poster Award & Reception
Mark Lemmon, PhD University of Pennsylvania Professor and Chair of Biochemistry and Biophysics
Richard DiMarchi, PhD Indiana University Standiford H. Cox Professor of Chemistry and the Linda & Jack Gill Chair in Biomolecular Sciences
Jonathan Moore, PhD Vertex Pharmaceuticals Senior Director
Sarah Hymowitz, PhD Genentech Associate Director: Structural Biology
Greg Miknis, PhD Colorado Center for Drug Discovery Associate Director
Guy Vigers, PhD Array BioPharma Senior Research Investigator
Xiaotian Zhu, PhD Ariad Pharmaceuticals Inc. Director
Thank you to our Sponsors!
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